FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PLC β2
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
150kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the Internal region of human PLC β2.
特异性
PLC β2 Polyclonal Antibody detects endogenous levels of PLC β2 protein.
基因名称
PLCB2
蛋白名称
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
别名
PLCB2;1-phosphatidylinositol 4;5-bisphosphate phosphodiesterase beta-2;Phosphoinositide phospholipase C-beta-2;Phospholipase C-beta-2;PLC-beta-2
Organism-1
Human
基因ID-1
5330
SwissProt-1
Q00722
Organism-2
Mouse
基因ID-2
18796
SwissProt-2
A3KGF7
Organism-3
Rat
基因ID-3
85240
SwissProt-3
O89040
背景
catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.,cofactor:Binds 1 calcium ion per subunit.,function:The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.,miscellaneous:The receptor-mediated activation of PLC-beta-2 is most effectively mediated by one G-protein alpha subunit, alpha-16.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PI-PLC X-box domain.,similarity:Contains 1 PI-PLC Y-box domain.,subunit:Interacts with RAC1.,
细胞定位
intracellular,cytosol,
