FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PKC
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
67-83kD(α 76,δ/β 77,γ 78,θ/ε83 ,ζ 67）
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PKC. AA range:623-672
特异性
PKC Polyclonal Antibody detects endogenous levels of PKC protein.
基因名称
PRKCA/PRKCB/PRKCD/PRKCE/PRKCG/PRKCH/PRKCQ/PRKCZ
蛋白名称
Protein kinase C alpha type/Protein kinase C beta type/Protein kinase C delta type/Protein kinase C epsilon type/Protein kinase C gamma type/Protein kinase C eta type/Protein kinase C theta type/Protein kinase C zeta type
别名
PRKCA;PKCA;PRKACA;Protein kinase C alpha type;PKC-A;PKC-alpha;PRKCB;PKCB;PRKCB1;Protein kinase C beta type;PKC-B;PKC-beta;PRKCD;Protein kinase C delta type;Tyrosine-protein kinase PRKCD;nPKC-delta;PRKCE;PKCE;Protein kinase
Organism-1
Human
基因ID-1
5578;5579;5580;5581;5582;5583;5588;5590
SwissProt-1
P17252;P05771;Q05655;Q02156;P05129;P24723;Q04759;Q05513
Organism-2
Mouse
基因ID-2
18750;18751;18753;18754
Organism-3
Rat
基因ID-3
25023;170538;29340
SwissProt-3
P05696;P68403;P09215;P09216
背景
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2
细胞定位
Cytoplasm . Cell membrane ; Peripheral membrane protein . Mitochondrion membrane ; Peripheral membrane protein . Nucleus .
