FGF-2 Polyclonal Antibody
¥680.00
PKA IIα reg Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2615759
- 产品信息
商品描述
靶点-Target
PKA IIα reg
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
45kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human KAP2. AA range:41-90
特异性
PKA IIα reg Polyclonal Antibody detects endogenous levels of PKA IIα reg protein.
基因名称
PRKAR2A
蛋白名称
cAMP-dependent protein kinase type II-alpha regulatory subunit
别名
PRKAR2A;PKR2;PRKAR2;cAMP-dependent protein kinase type II-alpha regulatory subunit
Organism-1
Human
基因ID-1
5576
SwissProt-1
P13861
Organism-2
Mouse
SwissProt-2
P12367
背景
protein kinase cAMP-dependent type II regulatory subunit alpha(PRKAR2A) Homo sapiens cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has b
细胞定位
Cytoplasm . Cell membrane . Colocalizes with PJA2 in the cytoplasm and the cell membrane.
