- 产品信息
商品描述
靶点-Target
PIPK I γ
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
80kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PIP5K1C. AA range:305-354
特异性
PIPK I γ Polyclonal Antibody detects endogenous levels of PIPK I γ protein.
基因名称
PIP5K1C
蛋白名称
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
别名
PIP5K1C;KIAA0589;Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma;PIP5K1-gamma;PtdIns;4;P-5-kinase 1 gamma;Phosphatidylinositol 4-phosphate 5-kinase type I gamma;PIP5KIgamma
Organism-1
Human
基因ID-1
23396
SwissProt-1
O60331
Organism-2
Mouse
SwissProt-2
O70161
背景
phosphatidylinositol-4-phosphate 5-kinase type 1 gamma(PIP5K1C) Homo sapiens This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Sep 2010],
细胞定位
Cell membrane; Peripheral membrane protein; Cytoplasmic side . Endomembrane system . Cytoplasm . Cell junction, focal adhesion . Cell junction, adherens junction . Cell projection, ruffle membrane . Cell projection, phagocytic cup . Cell projection, uropodium . Detected in plasma membrane invaginations. Isoform 3 is detected in intracellular vesicle-like structures.; [Isoform 2]: Cytoplasm. Nucleus.





