FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PinX1
反应性
Human,Rat,Mouse,
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
37kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PINX1. AA range:121-170
特异性
PinX1 Polyclonal Antibody detects endogenous levels of PinX1 protein.
基因名称
PINX1
蛋白名称
PIN2/TERF1-interacting telomerase inhibitor 1
别名
PINX1;LPTL;LPTS;PIN2/TERF1-interacting telomerase inhibitor 1;Liver-related putative tumor suppressor;Pin2-interacting protein X1;Protein 67-11-3;TRF1-interacting protein 1
Organism-1
Human
基因ID-1
54984
SwissProt-1
Q96BK5
Organism-2
Mouse
SwissProt-2
Q9CZX5
背景
domain:The TID (telomerase inhibiting domain) domain is sufficient to bind TERT and inhibit its activity.,function:Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.,similarity:Belongs to the PINX1 family.,similarity:Contains 1 G-patch domain.,subcellular location:In nucleoli and at telomere speckles.,subunit:Binds to MCRS1, TERT and TERF1.,tissue specificity:Ubiquitous; expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines.,
细胞定位
Nucleus . Nucleus, nucleolus. Chromosome, telomere. Chromosome, centromere, kinetochore. Localizes in nucleoli, at telomere speckles and to the outer plate of kinetochores. Localization to the kinetochore is mediated by its central region and depends on NDC80 and CENPE.
