FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PIAS 3
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
68kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PIAS3. AA range:10-59
特异性
PIAS 3 Polyclonal Antibody detects endogenous levels of PIAS 3 protein.
基因名称
PIAS3
蛋白名称
E3 SUMO-protein ligase PIAS3
别名
PIAS3;E3 SUMO-protein ligase PIAS3;Protein inhibitor of activated STAT protein 3
Organism-1
Human
基因ID-1
10401
SwissProt-1
Q9Y6X2
Organism-2
Mouse
基因ID-2
229615
SwissProt-2
O54714
Organism-3
Rat
基因ID-3
83614
SwissProt-3
O70260
背景
This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . Nucleus speckle . Colocalizes with MITF in the nucleus. Colocalizes with GFI1 in nuclear dots. Colocalizes with SUMO1 in nuclear granules. .
