PI 3-kinase p110α Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2615727
- 产品信息
商品描述
靶点-Target
PI 3-kinase p110α
反应性
Human,Mouse,Rat
应用
IF,WB,IHC,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
110kD
推荐稀释比
IF 1:50-200;WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;Not yet tested in other applications;
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PI 3-kinase p110alpha. AA range:470-519
特异性
PI 3-kinase p110α Polyclonal Antibody detects endogenous levels of PI 3-kinase p110α protein.
基因名称
PIK3CA
蛋白名称
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
别名
PIK3CA;Phosphatidylinositol 4;5-bisphosphate 3-kinase catalytic subunit alpha isoform;PI3-kinase subunit alpha;PI3K-alpha;PI3Kalpha;PtdIns-3-kinase subunit alpha;Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit
Organism-1
Human
基因ID-1
5290
SwissProt-1
P42336
Organism-2
Mouse
基因ID-2
18706
SwissProt-2
P42337
背景
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22. [provided by RefSeq, Apr 2016],
细胞定位
intracellular,cytosol,plasma membrane,phosphatidylinositol 3-kinase complex,phosphatidylinositol 3-kinase complex, class IA,lamellipodium,





