FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PHKB
反应性
Human,Mouse
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
124kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human KPBB. AA range:661-710
特异性
PHKB Polyclonal Antibody detects endogenous levels of PHKB protein.
基因名称
PHKB
蛋白名称
Phosphorylase b kinase regulatory subunit beta
别名
PHKB;Phosphorylase b kinase regulatory subunit beta;Phosphorylase kinase subunit beta
Organism-1
Human
基因ID-1
5257
SwissProt-1
Q93100
Organism-2
Mouse
基因ID-2
102093
SwissProt-2
Q7TSH2
背景
Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side .
