FGF-2 Polyclonal Antibody
¥680.00
PGI2 synthase Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2615708
- 产品信息
商品描述
靶点-Target
PGI2 synthase
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
57kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the C-terminal region of human PGI2 synthase.
特异性
PGI2 synthase Polyclonal Antibody detects endogenous levels of PGI2 synthase protein.
基因名称
PTGIS
蛋白名称
Prostacyclin synthase
别名
PTGIS;CYP8;CYP8A1;Prostacyclin synthase;Prostaglandin I2 synthase
Organism-1
Human
基因ID-1
5740
SwissProt-1
Q16647
Organism-2
Mouse
基因ID-2
19223
SwissProt-2
O35074
Organism-3
Rat
基因ID-3
25527
SwissProt-3
Q62969
背景
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008],
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein .
