PGE synthase Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2615707

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商品描述
  • 靶点-Target

    PGE synthase

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    17kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human PGE synthase. AA range:30-79

  • 特异性

    PGE synthase Polyclonal Antibody detects endogenous levels of PGE synthase protein.

  • 基因名称

    PTGES

  • 蛋白名称

    Prostaglandin E synthase

  • 别名

    PTGES;MGST1L1;MPGES1;PGES;PIG12;Prostaglandin E synthase;Microsomal glutathione S-transferase 1-like 1;MGST1-L1;Microsomal prostaglandin E synthase 1;MPGES-1;p53-induced gene 12 protein

  • Organism-1

    Human

  • 基因ID-1

    9536

  • SwissProt-1

    O14684

  • Organism-2

    Mouse

  • 基因ID-2

    64292

  • SwissProt-2

    Q9JM51

  • 背景

    prostaglandin E synthase(PTGES) Homo sapiens The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Membrane ; Multi-pass membrane protein . Cytoplasm, perinuclear region . Colocalizes with PTGS1/COX-1 and PTGS2/COX-2 in the perinuclear compartment. .