FGF-2 Polyclonal Antibody
¥680.00
PFK-2 liv Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2615701
- 产品信息
商品描述
靶点-Target
PFK-2 liv
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
58kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PFKFB1. AA range:406-455
特异性
PFK-2 liv Polyclonal Antibody detects endogenous levels of PFK-2 liv protein.
基因名称
PFKFB1
蛋白名称
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1
别名
PFKFB1;F6PK;PFRX;6-phosphofructo-2-kinase/fructose-2;6-bisphosphatase 1;6PF-2-K/Fru-2,6-P2ase 1;PFK/FBPase 1;6PF-2-K/Fru-2,6-P2ase liver isozyme
Organism-1
Human
基因ID-1
5207
SwissProt-1
P16118
Organism-2
Mouse
基因ID-2
18639
SwissProt-2
P70266
Organism-3
Rat
基因ID-3
24638
SwissProt-3
P07953
背景
This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012],
细胞定位
cytosol,6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex,
