FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PFKM
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
85kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PFK-1. AA range:320-369
特异性
PFKM Polyclonal Antibody detects endogenous levels of PFKM protein.
基因名称
PFKM
蛋白名称
6-phosphofructokinase muscle type
别名
PFKM;PFKX;6-phosphofructokinase;muscle type;Phosphofructo-1-kinase isozyme A;PFK-A;Phosphofructokinase-M;Phosphofructokinase 1;Phosphohexokinase
Organism-1
Human
基因ID-1
5213
SwissProt-1
P08237
Organism-2
Mouse
基因ID-2
18642
SwissProt-2
P47857
Organism-3
Rat
基因ID-3
65152
SwissProt-3
P47858
背景
Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009],
细胞定位
Cytoplasm .
