FGF-2 Polyclonal Antibody
¥680.00
Peroxin 5 Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2615696
- 产品信息
商品描述
靶点-Target
Peroxin 5
反应性
Human,Mouse
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from Peroxin 5 . at AA range: 540-620
特异性
Peroxin 5 Polyclonal Antibody detects endogenous levels of Peroxin 5 protein.
基因名称
PEX5
蛋白名称
Peroxisomal targeting signal 1 receptor
别名
PEX5;PXR1;Peroxisomal targeting signal 1 receptor;PTS1 receptor;PTS1R;PTS1-BP;Peroxin-5;Peroxisomal C-terminal targeting signal import receptor;Peroxisome receptor 1
Organism-1
Human
基因ID-1
5830
SwissProt-1
P50542
Organism-2
Mouse
基因ID-2
19305
SwissProt-2
O09012
背景
The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD)
细胞定位
Cytoplasm . Peroxisome membrane ; Peripheral membrane protein. Its distribution appears to be dynamic. It is probably a cycling receptor found mainly in the cytoplasm and as well associated to the peroxisomal membrane through a docking factor (PEX13).
