Peroxin 19 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2615693
- 产品信息
商品描述
靶点-Target
Peroxin 19
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
33kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PEX19. AA range:219-268
特异性
Peroxin 19 Polyclonal Antibody detects endogenous levels of Peroxin 19 protein.
基因名称
PEX19
蛋白名称
Peroxisomal biogenesis factor 19
别名
PEX19;HK33;PXF;OK/SW-cl.22;Peroxisomal biogenesis factor 19;33 kDa housekeeping protein;Peroxin-19;Peroxisomal farnesylated protein
Organism-1
Human
基因ID-1
5824
SwissProt-1
P40855
Organism-2
Mouse
SwissProt-2
Q8VCI5
背景
peroxisomal biogenesis factor 19(PEX19) Homo sapiens This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is
细胞定位
Cytoplasm . Peroxisome membrane ; Lipid-anchor ; Cytoplasmic side . Mainly cytoplasmic. Some fraction membrane-associated to the outer surface of peroxisomes. .





