FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Per3
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
130kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PER3. AA range:21-70
特异性
Per3 Polyclonal Antibody detects endogenous levels of Per3 protein.
基因名称
PER3
蛋白名称
Period circadian protein homolog 3
别名
PER3;GIG13;Period circadian protein homolog 3;hPER3;Cell growth-inhibiting gene 13 protein;Circadian clock protein PERIOD 3
Organism-1
Human
基因ID-1
8863
SwissProt-1
P56645
Organism-2
Mouse
SwissProt-2
O70361
背景
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014],
细胞定位
Cytoplasm . Nucleus . Mainly cytoplasmic. Translocates to the nucleus through binding PER1, PER2, CRY1 or CRY2, but not TIMELESS. .
