FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PEG3
反应性
Human,Mouse
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
181kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PEG3. AA range:1031-1080
特异性
PEG3 Polyclonal Antibody detects endogenous levels of PEG3 protein.
基因名称
PEG3
蛋白名称
Paternally-expressed gene 3 protein
别名
PEG3;KIAA0287;ZSCAN24;Paternally-expressed gene 3 protein;Zinc finger and SCAN domain-containing protein 24
Organism-1
Human
基因ID-1
5178
SwissProt-1
Q9GZU2
Organism-2
Mouse
SwissProt-2
Q3URU2
背景
In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2009],
细胞定位
Nucleus . Cytoplasm .
