- 产品信息
商品描述
靶点-Target
PEA-15
反应性
Human,Mouse,Rat,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
36kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PEA-15. AA range:81-130
特异性
PEA-15 Polyclonal Antibody detects endogenous levels of PEA-15 protein.
基因名称
PEA15
蛋白名称
Astrocytic phosphoprotein PEA-15
别名
PEA15;Astrocytic phosphoprotein PEA-15;15 kDa phosphoprotein enriched in astrocytes;Phosphoprotein enriched in diabetes;PED
Organism-1
Human
基因ID-1
8682
SwissProt-1
Q15121
Organism-2
Mouse
基因ID-2
18611
SwissProt-2
Q62048
Organism-3
Rat
基因ID-3
364052
SwissProt-3
Q5U318
背景
phosphoprotein enriched in astrocytes 15(PEA15) Homo sapiens This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
细胞定位
Cytoplasm. Associated with microtubules.





