FGF-2 Polyclonal Antibody
¥680.00
PDZ-RhoGEF Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
一键复制产品信息
产品规格：
- 50μL
- 100μL
货号：
FAB2615674
- 产品信息
商品描述
靶点-Target
PDZ-RhoGEF
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
168kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ARHGEF11. AA range:198-247
特异性
PDZ-RhoGEF Polyclonal Antibody detects endogenous levels of PDZ-RhoGEF protein.
基因名称
ARHGEF11
蛋白名称
Rho guanine nucleotide exchange factor 11
别名
ARHGEF11;KIAA0380;Rho guanine nucleotide exchange factor 11;PDZ-RhoGEF
Organism-1
Human
基因ID-1
9826
SwissProt-1
O15085
Organism-3
Rat
基因ID-3
78966
SwissProt-3
Q9ES67
背景
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Membrane . Translocated to the membrane upon stimulation.
