FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PDX1
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
42kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PDX1. AA range:27-76
特异性
PDX-1 Polyclonal Antibody detects endogenous levels of PDX-1 protein.
基因名称
PDX1
蛋白名称
Pancreas/duodenum homeobox protein 1
别名
PDX1;IPF1;Pancreas/duodenum homeobox protein 1;PDX-1;Glucose-sensitive factor;GSF;Insulin promoter factor 1;IPF-1;Insulin upstream factor 1;IUF-1;Islet/duodenum homeobox-1;IDX-1;Somatostatin-transactivating factor 1;STF-1
Organism-1
Human
基因ID-1
3651
SwissProt-1
P52945
Organism-2
Mouse
基因ID-2
18609
SwissProt-2
P52946
Organism-3
Rat
基因ID-3
29535
SwissProt-3
P52947
背景
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Jul 2008],
细胞定位
Nucleus. Cytoplasm, cytosol .
