- 产品信息
商品描述
靶点-Target
PDK2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
46kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PDK2. AA range:260-309
特异性
PDK2 Polyclonal Antibody detects endogenous levels of PDK2 protein.
基因名称
PDK2
蛋白名称
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2 mitochondrial
别名
PDK2;PDHK2;[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2;mitochondrial;Pyruvate dehydrogenase kinase isoform 2
Organism-1
Human
基因ID-1
5164
SwissProt-1
Q15119
Organism-2
Mouse
基因ID-2
18604
SwissProt-2
Q9JK42
Organism-3
Rat
基因ID-3
81530
SwissProt-3
Q64536
背景
This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],
细胞定位
Mitochondrion matrix.





