- 产品信息
商品描述
靶点-Target
PDE4C
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
80kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PDE4C. AA range:291-340
特异性
PDE4C Polyclonal Antibody detects endogenous levels of PDE4C protein.
基因名称
PDE4C
蛋白名称
cAMP-specific 3',5'-cyclic phosphodiesterase 4C
别名
PDE4C;DPDE1;cAMP-specific 3';5'-cyclic phosphodiesterase 4C;DPDE1;PDE21
Organism-1
Human
基因ID-1
5143
SwissProt-1
Q08493
Organism-2
Mouse
基因ID-2
110385
SwissProt-2
Q3UEI1
Organism-3
Rat
SwissProt-3
P14644
背景
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011],
细胞定位
Cell projection, cilium .





