- 产品信息
商品描述
靶点-Target
PDE10A
反应性
Human,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
75kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PDE10A. AA range:21-70
特异性
PDE10A Polyclonal Antibody detects endogenous levels of PDE10A protein.
基因名称
PDE10A
蛋白名称
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
别名
PDE10A;cAMP and cAMP-inhibited cGMP 3';5'-cyclic phosphodiesterase 10A
Organism-1
Human
基因ID-1
10846
SwissProt-1
Q9Y233
Organism-2
Mouse
SwissProt-2
Q8CA95
Organism-3
Rat
基因ID-3
63885
SwissProt-3
Q9QYJ6
背景
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011],
细胞定位
Cytoplasm, cytosol .





