FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PCB
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
120kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:100-300;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PC. AA range:357-406
特异性
PCB Polyclonal Antibody detects endogenous levels of PCB protein.
基因名称
PC
蛋白名称
Pyruvate carboxylase mitochondrial
别名
PC;Pyruvate carboxylase;mitochondrial;Pyruvic carboxylase;PCB
Organism-1
Human
基因ID-1
5091
SwissProt-1
P11498
Organism-2
Mouse
SwissProt-2
Q05920
Organism-3
Rat
基因ID-3
25104
SwissProt-3
P52873
背景
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion matrix .
