FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Patched
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
160kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Patched. AA range:1-50
特异性
Patched Polyclonal Antibody detects endogenous levels of Patched protein.
基因名称
PTCH1
蛋白名称
Protein patched homolog 1
别名
PTCH1;PTCH;Protein patched homolog 1;PTC;PTC1
Organism-1
Human
基因ID-1
5727
SwissProt-1
Q13635
Organism-2
Mouse
基因ID-2
19206
SwissProt-2
Q61115
背景
This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Multi-pass membrane protein .
