FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PARP-3
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
60kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PARP3. AA range:10-59
特异性
PARP-3 Polyclonal Antibody detects endogenous levels of PARP-3 protein.
基因名称
PARP3
蛋白名称
Poly [ADP-ribose] polymerase 3
别名
PARP3;ADPRT3;ADPRTL3;Poly [ADP-ribose] polymerase 3;PARP-3;hPARP-3;ADP-ribosyltransferase diphtheria toxin-like 3;ARTD3;IRT1;NAD;+;ADP-ribosyltransferase 3;ADPRT-3;Poly[ADP-ribose] synthase 3;pADPRT-3
Organism-1
Human
基因ID-1
10039
SwissProt-1
Q9Y6F1
背景
The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Chromosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Almost exclusively localized in the nucleus and appears in numerous small foci and a small number of larger foci whereas a centrosomal location has not been detected (PubMed:16924674). In response to DNA damage, localizes to sites of double-strand break (PubMed:21270334). Preferentially localized to the daughter centriole (PubMed:10329013). .
