PARP-2 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2615629

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商品描述
  • 靶点-Target

    PARP-2

  • 反应性

    Human,Mouse

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    75kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human PARP2. AA range:151-200

  • 特异性

    PARP-2 Polyclonal Antibody detects endogenous levels of PARP-2 protein.

  • 基因名称

    PARP2

  • 蛋白名称

    Poly [ADP-ribose] polymerase 2

  • 别名

    PARP2;ADPRT2;ADPRTL2;Poly [ADP-ribose] polymerase 2;PARP-2;hPARP-2;ADP-ribosyltransferase diphtheria toxin-like 2;ARTD2;NAD;+;ADP-ribosyltransferase 2;ADPRT-2;Poly[ADP-ribose] synthase 2;pADPRT-2

  • Organism-1

    Human

  • 基因ID-1

    10038

  • SwissProt-1

    Q9UGN5

  • Organism-2

    Mouse

  • 基因ID-2

    11546

  • SwissProt-2

    O88554

  • 背景

    This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Nucleus . Chromosome . Recruited to DNA damage sites. .