- 产品信息
商品描述
靶点-Target
PARP-2
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
75kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PARP2. AA range:151-200
特异性
PARP-2 Polyclonal Antibody detects endogenous levels of PARP-2 protein.
基因名称
PARP2
蛋白名称
Poly [ADP-ribose] polymerase 2
别名
PARP2;ADPRT2;ADPRTL2;Poly [ADP-ribose] polymerase 2;PARP-2;hPARP-2;ADP-ribosyltransferase diphtheria toxin-like 2;ARTD2;NAD;+;ADP-ribosyltransferase 2;ADPRT-2;Poly[ADP-ribose] synthase 2;pADPRT-2
Organism-1
Human
基因ID-1
10038
SwissProt-1
Q9UGN5
Organism-2
Mouse
基因ID-2
11546
SwissProt-2
O88554
背景
This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Chromosome . Recruited to DNA damage sites. .





