FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PARD3A
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
151kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PARD3. AA range:1141-1190
特异性
PARD3A Polyclonal Antibody detects endogenous levels of PARD3A protein.
基因名称
PARD3
蛋白名称
Partitioning defective 3 homolog
别名
PARD3;PAR3;PAR3A;Partitioning defective 3 homolog;PAR-3;PARD-3;Atypical PKC isotype-specific-interacting protein;ASIP;CTCL tumor antigen se2-5;PAR3-alpha
Organism-1
Human
基因ID-1
56288
SwissProt-1
Q8TEW0
Organism-2
Mouse
基因ID-2
93742
SwissProt-2
Q99NH2
Organism-3
Rat
基因ID-3
81918
SwissProt-3
Q9Z340
背景
This gene encodes a member of the PARD protein family. PARD family members interact with other PARD family members and other proteins; they affect asymmetrical cell division and direct polarized cell growth. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011],
细胞定位
Cytoplasm . Endomembrane system . Cell junction . Cell junction, tight junction . Cell junction, adherens junction . Cell membrane . Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Localized along the cell-cell contact region. Colocalizes with PARD6A and PRKCI at epithelial tight junctions. Colocalizes with the cortical actin that overlays the meiotic spindle during metaphase I and metaphase II. Colocalized with SIRT2 in internode region of myelin sheath (By similarity). Presence of KRIT1, CDH5 and RAP1B is required for its localization to the cell junction. .
