- 产品信息
商品描述
靶点-Target
PAI-3
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
42kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Serpin A5. AA range:260-309
特异性
PAI-3 Polyclonal Antibody detects endogenous levels of PAI-3 protein.
基因名称
SERPINA5
蛋白名称
Plasma serine protease inhibitor
别名
SERPINA5;PCI;PLANH3;Plasma serine protease inhibitor;Acrosomal serine protease inhibitor;Plasminogen activator inhibitor 3;PAI-3;PAI3;Protein C inhibitor;PCI;Serpin A5
Organism-1
Human
基因ID-1
155698
SwissProt-1
P05154
Organism-2
Mouse
SwissProt-2
P70458
背景
The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. This family member is a glycoprotein that can inhibit several serine proteases, including protein C and various plasminogen activators and kallikreins, and it thus plays diverse roles in hemostasis and thrombosis in multiple organs. [provided by RefSeq, Aug 2012],
细胞定位
Secreted, extracellular space . Localized on the plasma membrane overlying the acrosomal head of spermatozoa of ependymal spermatozoa and ejaculated sperm. Localized at the equatorial segment of acrosome-reacted spematozoa. Localized in alpha granules in resting platelets and on the external plasma membrane and within the surface-connected cannalicular system in activated platelets.





