FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PA26
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
57kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SESN1. AA range:271-320
特异性
PA26 Polyclonal Antibody detects endogenous levels of PA26 protein.
基因名称
SESN1
蛋白名称
Sestrin-1
别名
SESN1;PA26;SEST1;Sestrin-1;p53-regulated protein PA26
Organism-1
Human
基因ID-1
27244
SwissProt-1
Q9Y6P5
Organism-2
Mouse
基因ID-2
140742
SwissProt-2
P58006
背景
This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],
细胞定位
Nucleus . Cytoplasm .
