FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
p53R2
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
40kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the Internal region of human p53R2.
特异性
p53R2 Polyclonal Antibody detects endogenous levels of p53R2 protein.
基因名称
RRM2B
蛋白名称
Ribonucleoside-diphosphate reductase subunit M2 B
别名
RRM2B;P53R2;Ribonucleoside-diphosphate reductase subunit M2 B;TP53-inducible ribonucleotide reductase M2 B;p53-inducible ribonucleotide reductase small subunit 2-like protein;p53R2
Organism-1
Human
基因ID-1
50484
SwissProt-1
Q7LG56
Organism-2
Mouse
基因ID-2
382985
SwissProt-2
Q6PEE3
背景
This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010],
细胞定位
Cytoplasm. Nucleus. Translocates from cytoplasm to nucleus in response to DNA damage.
