p52 S6 kinase Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2615591

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商品描述
  • 靶点-Target

    p52 S6 kinase

  • 反应性

    Human,Mouse

  • 应用

    WB,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    117kD

  • 推荐稀释比

    WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human RPS6KC1. AA range:231-280

  • 特异性

    p52 S6 kinase Polyclonal Antibody detects endogenous levels of p52 S6 kinase protein.

  • 基因名称

    RPS6KC1

  • 蛋白名称

    Ribosomal protein S6 kinase delta-1

  • 别名

    RPS6KC1;RPK118;Ribosomal protein S6 kinase delta-1;S6K-delta-1;52 kDa ribosomal protein S6 kinase;Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein;SPHK1-binding protein

  • Organism-1

    Human

  • 基因ID-1

    26750

  • SwissProt-1

    Q96S38

  • Organism-2

    Mouse

  • 基因ID-2

    320119

  • SwissProt-2

    Q8BLK9

  • 背景

    catalytic activity:ATP + a protein = ADP + a phosphoprotein.,caution:Instead of Lys-820, Arg-820 is found at the binding site.,domain:The first protein kinase domain appears to be a pseudokinase domain as it does not contain the classical characteristics, such as the ATP-binding motif, ATP-binding site and active site.,function:May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 MIT domain.,similarity:Contains 1 PX (phox homology) domain.,similarity:Contains 2 protein kinase domains.,subcellular location:Also found in some small dot-like or ring-shaped early endosome structures.,subunit:Interacts with SPHK1 and phosphatidylinositol 3-phosphate.,tissue specificity:Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon.,

  • 细胞定位

    Cytoplasm . Membrane . Early endosome .