FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
P311
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
8kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human C5orf13. AA range:13-62
特异性
P311 Polyclonal Antibody detects endogenous levels of P311 protein.
基因名称
NREP
蛋白名称
Neuronal regeneration-related protein
别名
NREP;C5orf13;P311;Neuronal regeneration-related protein;Neuronal protein 3.1;Protein p311
Organism-1
Human
基因ID-1
9315
SwissProt-1
Q16612
Organism-2
Mouse
基因ID-2
27528
SwissProt-2
Q07475
Organism-3
Rat
基因ID-3
338475
SwissProt-3
Q80Z34
背景
P311, also known as C5orf13 (chromosome 5 open reading frame 13), D4S114, PTZ17 or PRO1873, is a 68 amino acid cytoplasmic protein involved in cellular differentiation, neural function and axonal regeneration. Found in the granular layer of the cerebellum, P311 is expressed at lower levels in hippocampus, olfactory bulb, kidney, liver and heart and when expressed ectopically, P311 augments giloma motility. P311 is enriched in mice within the superficial cortical layers and striatum at E20 and the germinal zones at E17. Known to interact with Filamin 1, P311 regulates retinoic-acid lipid-droplet biogenesis, induces myofibroblast ameboid migration and the differentiation of fibroblasts into myofibroblasts. Ser-59 phosphorylation decreases P311 stability; the gene encoding P311 maps to human chromosome 5q22.
细胞定位
Cytoplasm .
