FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
p19
反应性
Human,Mouse
应用
IHC,IF,WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
18kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CDKN2D. AA range:96-145
特异性
p19 Polyclonal Antibody detects endogenous levels of p19 protein.
基因名称
CDKN2D
蛋白名称
Cyclin-dependent kinase 4 inhibitor D
别名
CDKN2D;Cyclin-dependent kinase 4 inhibitor D;p19-INK4d
Organism-1
Human
基因ID-1
1032
SwissProt-1
P55273
Organism-2
Mouse
SwissProt-2
Q60773
背景
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm .
