FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
p140Cap
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
112kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SNIP. AA range:811-860
特异性
p140Cap Polyclonal Antibody detects endogenous levels of p140Cap protein.
基因名称
SRCIN1
蛋白名称
SRC kinase signaling inhibitor 1
别名
SRCIN1;KIAA1684;P140;SRC kinase signaling inhibitor 1;SNAP-25-interacting protein;SNIP;p130Cas-associated protein;p140Cap
Organism-1
Human
基因ID-1
80725
SwissProt-1
Q9C0H9
Organism-2
Mouse
基因ID-2
56013
SwissProt-2
Q9QWI6
Organism-3
Rat
基因ID-3
56029
SwissProt-3
Q9QXY2
背景
function:Delays the onset of cell spreading in the early stages of cell adhesion to fibronectin. Also involved in calcium-dependent exocytosis from PC12 cells.,PTM:Tyrosine-phosphorylated in response to EGF and to cell adhesion to integrin ligands.,similarity:Belongs to the p140Cap family.,subcellular location:Localized to the perinuclear region, lamellopodia, cortical actin and actin stress fibers but not to focal adhesions.,subunit:Interacts with the N-terminal coiled-coil region of SNAP25 (By similarity). Interacts with BCAR1/p130Cas through its C-terminal domain.,
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton . Cell projection, axon . Cell projection, dendrite . Cell junction, synapse, presynapse . Cell junction, synapse, postsynapse . Cell junction, synapse, postsynaptic density . Localized to the perinuclear region, lamellopodia, cortical actin and actin stress fibers but not to focal adhesions. Strongly expressed in axons and dendrites of the CA1 and CA3 hippocampal regions and of the dentate gyrus. Detected in both presynapses and postsynapses and enriched in postsynaptic density fractions. .
