- 产品信息
商品描述
靶点-Target
OTUD2
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
35kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human YOD1. AA range:116-165
特异性
OTUD2 Polyclonal Antibody detects endogenous levels of OTUD2 protein.
基因名称
YOD1
蛋白名称
Ubiquitin thioesterase OTU1
别名
YOD1;DUBA8;HIN7;OTUD2;Ubiquitin thioesterase OTU1;DUBA-8;HIV-1-induced protease 7;HIN-7;HsHIN7;OTU domain-containing protein 2
Organism-1
Human
基因ID-1
55432
SwissProt-1
Q5VVQ6
Organism-2
Mouse
SwissProt-2
Q8CB27
背景
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. The protein encoded by this gene belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],
细胞定位
Cytoplasm . Recruited to damaged lysosomes decorated with K48-linked ubiquitin chains. .





