FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ORCTL2
反应性
Human,Rat,Mouse,
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
43kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ORCTL-2. AA range:359-408
特异性
ORCTL2 Polyclonal Antibody detects endogenous levels of ORCTL2 protein.
基因名称
SLC22A18
蛋白名称
Solute carrier family 22 member 18
别名
SLC22A18;BWR1A;BWSCR1A;HET;IMPT1;ITM;ORCTL2;SLC22A1L;TSSC5;Solute carrier family 22 member 18;Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein;Efflux transporter-like protein;Imprinted multi-membrane-spa
Organism-1
Human
基因ID-1
5002
SwissProt-1
Q96BI1
Organism-2
Mouse
SwissProt-2
Q78KK3
背景
This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is imprinted, with preferential expression from the maternal allele. Mutations in this gene have been found in Wilms' tumor and lung cancer. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Several alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2015],
细胞定位
Apical cell membrane ; Multi-pass membrane protein . Localized at the apical membrane surface of renal proximal tubules. .
