OCTN2 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2615323

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商品描述
  • 靶点-Target

    OCTN2

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    65kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human SLC22A5. AA range:300-349

  • 特异性

    OCTN2 Polyclonal Antibody detects endogenous levels of OCTN2 protein.

  • 基因名称

    SLC22A5

  • 蛋白名称

    Solute carrier family 22 member 5

  • 别名

    SLC22A5;OCTN2;Solute carrier family 22 member 5;High-affinity sodium-dependent carnitine cotransporter;Organic cation/carnitine transporter 2

  • Organism-1

    Human

  • 基因ID-1

    6584

  • SwissProt-1

    O76082

  • Organism-2

    Mouse

  • SwissProt-2

    Q9Z0E8

  • 背景

    Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015],

  • 细胞定位

    Membrane ; Multi-pass membrane protein .