- 产品信息
商品描述
靶点-Target
OATP-C
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
76kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SLCO1B1. AA range:251-300
特异性
OATP-C Polyclonal Antibody detects endogenous levels of OATP-C protein.
基因名称
SLCO1B1
蛋白名称
Solute carrier organic anion transporter family member 1B1
别名
SLCO1B1;LST1;OATP1B1;OATP2;OATPC;SLC21A6;Solute carrier organic anion transporter family member 1B1;Liver-specific organic anion transporter 1;LST-1;OATP-C;Sodium-independent organic anion-transporting polypeptide 2;OATP-2;Solut
Organism-1
Human
基因ID-1
10599
SwissProt-1
Q9Y6L6
背景
This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009],
细胞定位
Basolateral cell membrane ; Multi-pass membrane protein . Detected in basolateral membranes of hepatocytes.





