- 产品信息
商品描述
靶点-Target
NUDC
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NudC. AA range:282-331
特异性
NUDC Polyclonal Antibody detects endogenous levels of NUDC protein.
基因名称
NUDC
蛋白名称
Nuclear migration protein nudC
别名
NUDC;Nuclear migration protein nudC;Nuclear distribution protein C homolog
Organism-1
Human
基因ID-1
10726
SwissProt-1
Q9Y266
Organism-2
Mouse
基因ID-2
18221
SwissProt-2
O35685
Organism-3
Rat
基因ID-3
29648
SwissProt-3
Q63525
背景
This gene encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded protein is involved in spindle formation during mitosis and in microtubule organization during cytokinesis. Pseudogenes of this gene are found on chromosome 2. [provided by RefSeq, Feb 2012],
细胞定位
Cytoplasm, cytoskeleton. Nucleus . Cytoplasm, cytoskeleton, spindle . Midbody . In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern. Localizes to the mitotic spindle in a EML4-dependent manner (PubMed:25789526). .





