- 产品信息
商品描述
靶点-Target
NTR2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
45kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NTR2. AA range:151-200
特异性
NTR2 Polyclonal Antibody detects endogenous levels of NTR2 protein.
基因名称
NTSR2
蛋白名称
Neurotensin receptor type 2
别名
NTSR2;Neurotensin receptor type 2;NT-R-2;NTR2;Levocabastine-sensitive neurotensin receptor
Organism-1
Human
基因ID-1
23620
SwissProt-1
O95665
Organism-2
Mouse
SwissProt-2
P70310
Organism-3
Rat
基因ID-3
64636
SwissProt-3
Q63384
背景
The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane; Multi-pass membrane protein.





