- 产品信息
商品描述
靶点-Target
NRF-1
反应性
Human,Mouse,Rat,Bovine
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
54kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NRF1. AA range:221-270
特异性
NRF-1 Polyclonal Antibody detects endogenous levels of NRF-1 protein.
基因名称
NRF1
蛋白名称
Nuclear respiratory factor 1
别名
NRF1;Nuclear respiratory factor 1;NRF-1;Alpha palindromic-binding protein;Alpha-pal
Organism-1
Human
基因ID-1
4899
SwissProt-1
Q16656
Organism-2
Mouse
基因ID-2
18181
SwissProt-2
Q9WU00
Organism-3
Rat
SwissProt-3
Q62792
背景
This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014],
细胞定位
Nucleus.





