FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NQO1
反应性
Human,Rat,Mouse,
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
31kD
推荐稀释比
WB 1:500-1:2000;IF 1:50-200;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NQO1. AA range:203-252
特异性
NQO1 Polyclonal Antibody detects endogenous levels of NQO1 protein.
基因名称
NQO1
蛋白名称
NAD(P)H dehydrogenase [quinone] 1
别名
NQO1;DIA4;NMOR1;NAD;P;H dehydrogenase [quinone] 1;Azoreductase;DT-diaphorase;DTD;Menadione reductase;NAD;P;H:quinone oxidoreductase 1;Phylloquinone reductase;Quinone reductase 1;QR1
Organism-1
Human
基因ID-1
1728
SwissProt-1
P15559
Organism-2
Mouse
SwissProt-2
Q64669
背景
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, cytosol .
