FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NPY
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
11kD
推荐稀释比
IHC 1:100-500;WB 1:500-2000;ELISA 1:5000-20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NPY. AA range:45-94
特异性
NPY Polyclonal Antibody detects endogenous levels of NPY protein.
基因名称
NPY
蛋白名称
Pro-neuropeptide Y
别名
NPY;Pro-neuropeptide Y
Organism-1
Human
基因ID-1
4852
SwissProt-1
P01303
Organism-2
Mouse
基因ID-2
109648
SwissProt-2
P57774
Organism-3
Rat
基因ID-3
100912228
SwissProt-3
P07808
背景
This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014],
细胞定位
Secreted. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle .
