FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Nopp140
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
74kD,130kD(Nucleolar phosphoprotein p130)
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from Nopp140 . at AA range: 620-700
特异性
Nopp140 Polyclonal Antibody detects endogenous levels of Nopp140 protein.
基因名称
NOLC1
蛋白名称
Nucleolar and coiled-body phosphoprotein 1
别名
NOLC1;KIAA0035;NS5ATP13;Nucleolar and coiled-body phosphoprotein 1;140 kDa nucleolar phosphoprotein;Nopp140;Hepatitis C virus NS5A-transactivated protein 13;HCV NS5A-transactivated protein 13;Nucleolar 130 kDa protein;Nucleolar pho
Organism-1
Human
基因ID-1
9221
SwissProt-1
Q14978
Organism-3
Rat
基因ID-3
64896
SwissProt-3
P41777
背景
function:Related to nucleologenesis, may play a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. May play an important role in transcription catalyzed by RNA polymerase I.,PTM:Undergoes rapid and massive phosphorylation/dephosphorylation cycles on CK2 and PKC sites. There is evidence suggesting that CDC2 kinase phosphorylates p130 at the M-phase.,similarity:Contains 1 LisH domain.,subcellular location:Shuttles between the nucleolus and the cytoplasm. At telophase it begins to assemble into granular-like pre-nucleolar bodies which are subsequently relocated to nucleoli at the early G1-phase.,subunit:Interacts with RNA polymerase I 194 kDa subunit (RPA194) and with casein kinase-II.,
细胞定位
Nucleus, nucleolus . Cytoplasm . Shuttles between the nucleolus and the cytoplasm. At telophase it begins to assemble into granular-like pre-nucleolar bodies which are subsequently relocated to nucleoli at the early G1-phase. .
