- 产品信息
商品描述
靶点-Target
NMBR
反应性
Human,Mouse,Rat
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
43kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NMBR. AA range:221-270
特异性
NMBR Polyclonal Antibody detects endogenous levels of NMBR protein.
基因名称
NMBR
蛋白名称
Neuromedin-B receptor
别名
NMBR;Neuromedin-B receptor;NMB-R;Epididymis tissue protein Li 185a;Neuromedin-B-preferring bombesin receptor
Organism-1
Human
基因ID-1
4829
SwissProt-1
P28336
Organism-2
Mouse
基因ID-2
18101
SwissProt-2
O54799
Organism-3
Rat
基因ID-3
25264
SwissProt-3
P24053
背景
This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016],
细胞定位
Cell membrane ; Multi-pass membrane protein .





