NMBR Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2615251

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商品描述
  • 靶点-Target

    NMBR

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    43kD

  • 推荐稀释比

    WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human NMBR. AA range:221-270

  • 特异性

    NMBR Polyclonal Antibody detects endogenous levels of NMBR protein.

  • 基因名称

    NMBR

  • 蛋白名称

    Neuromedin-B receptor

  • 别名

    NMBR;Neuromedin-B receptor;NMB-R;Epididymis tissue protein Li 185a;Neuromedin-B-preferring bombesin receptor

  • Organism-1

    Human

  • 基因ID-1

    4829

  • SwissProt-1

    P28336

  • Organism-2

    Mouse

  • 基因ID-2

    18101

  • SwissProt-2

    O54799

  • Organism-3

    Rat

  • 基因ID-3

    25264

  • SwissProt-3

    P24053

  • 背景

    This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016],

  • 细胞定位

    Cell membrane ; Multi-pass membrane protein .