FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NM23-H2
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
23kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NM23. AA range:91-140
特异性
NM23-H2 Polyclonal Antibody detects endogenous levels of NM23-H2 protein.
基因名称
NME2
蛋白名称
Nucleoside diphosphate kinase B
别名
NME2;NM23B;Nucleoside diphosphate kinase B;NDK B;NDP kinase B;C-myc purine-binding transcription factor PUF;Histidine protein kinase NDKB;nm23-H2
Organism-1
Human
基因ID-1
4831;654364
SwissProt-1
P22392
Organism-2
Mouse
基因ID-2
18103
SwissProt-2
Q01768
Organism-3
Rat
基因ID-3
83782
SwissProt-3
P19804
背景
Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Nov 2010],
细胞定位
Cytoplasm . Cell projection, lamellipodium . Cell projection, ruffle . Colocalizes with ITGB1 and ITGB1BP1 at the edge or peripheral ruffles and lamellipodia during the early stages of cell spreading on fibronectin or collagen but not on vitronectin or laminin substrates. .; [Isoform 1]: Cytoplasm . Cytoplasm, perinuclear region . Nucleus .; [Isoform 3]: Cytoplasm . Cytoplasm, perinuclear region . Nucleus .
