FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NM23-H1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
23kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NM23-H1. AA range:3-52
特异性
NM23-H1 Polyclonal Antibody detects endogenous levels of NM23-H1 protein.
基因名称
NME1
蛋白名称
Nucleoside diphosphate kinase A
别名
NME1;NDPKA;NM23;Nucleoside diphosphate kinase A;NDK A;NDP kinase A;Granzyme A-activated DNase;GAAD;Metastasis inhibition factor nm23;Tumor metastatic process-associated protein;nm23-H1
Organism-1
Human
基因ID-1
4830
SwissProt-1
P15531
Organism-2
Mouse
基因ID-2
18102
SwissProt-2
P15532
Organism-3
Rat
基因ID-3
191575
SwissProt-3
Q05982
背景
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . Cell-cycle dependent nuclear localization which can be induced by interaction with Epstein-barr viral proteins or by degradation of the SET complex by GzmA.
