FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NIPP1
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
40kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PPP1R8. AA range:196-245
特异性
NIPP1 Polyclonal Antibody detects endogenous levels of NIPP1 protein.
基因名称
PPP1R8
蛋白名称
Nuclear inhibitor of protein phosphatase 1
别名
PPP1R8;ARD1;NIPP1;Nuclear inhibitor of protein phosphatase 1;NIPP-1;Protein phosphatase 1 regulatory inhibitor subunit 8
Organism-1
Human
基因ID-1
5511
SwissProt-1
Q12972
Organism-2
Mouse
基因ID-2
100336
SwissProt-2
Q8R3G1
背景
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus. Nucleus speckle. Primarily, but not exclusively, nuclear.; [Isoform Gamma]: Cytoplasm. Found mainly in the cytoplasm.
