- 产品信息
商品描述
靶点-Target
Nicalin
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
63kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NCLN. AA range:474-523
特异性
Nicalin Polyclonal Antibody detects endogenous levels of Nicalin protein.
基因名称
NCLN
蛋白名称
Nicalin
别名
NCLN;Nicalin;Nicastrin-like protein
Organism-1
Human
基因ID-1
56926
SwissProt-1
Q969V3
Organism-2
Mouse
基因ID-2
103425
SwissProt-2
Q8VCM8
Organism-3
Rat
基因ID-3
314648
SwissProt-3
Q5XIA1
背景
function:May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.,similarity:Belongs to the nicastrin family.,subunit:Interacts with NOMO2. Due to the strong similarity between NOMO1, NOMO2 and NOMO3, it probably also interacts with NOMO1 and NOMO3. Participates in a large protein complex, which is not related to the gamma-secretase complex.,tissue specificity:Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart.,
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein .





