FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NGF
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
27kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:100-300;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NGF. AA range:33-82
特异性
NGF Polyclonal Antibody detects endogenous levels of NGF protein.
基因名称
NGF
蛋白名称
Beta-nerve growth factor
别名
NGF;NGFB;Beta-nerve growth factor;Beta-NGF
Organism-1
Human
基因ID-1
4803
SwissProt-1
P01138
Organism-2
Mouse
基因ID-2
18049
SwissProt-2
P01139
Organism-3
Rat
基因ID-3
310738
SwissProt-3
P25427
背景
This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. [provided by RefSeq, Jul 2008],
细胞定位
Secreted . Endosome lumen . ProNGF is endocytosed after binding to the cell surface receptor formed by SORT1 and NGFR. .
